Remove the outer plastic protective wrapping from the applicator bottle. Unscrew the white bottle cap by holding the base and twisting counter-clockwise. Remove the inner foil seal to open for first-time use. Replace the white cap and screw on tightly. Next, to apply the Activator solution, open the dispenser portion of the cap by turning the upper portion of the cap clockwise. Apply a small amount of the Activator solution by placing the open tip onto thinning areas of your scalp. Apply gentle pressure to the bottle until you feel enough fluid has been released to massage it over thinning areas. Massage Activator solution into skin and then follow by combing or brushing your hair.